Biography

I'm a software engineer working (since Jan 2014) as Project Manager for Orobix Srl. I'm currently involved in different research activities such as software design and develop on cloud-based computing technologies, 3D computer graphics and image rendering, image analysis and motion-sensing technologies.

From April 2009 to December 2013 I worked as a researcher in the Medical Imaging Unit of the Biomedical Engineering Department of the Mario Negri Institute, a no-profit italian research organization. My working interests were focused on software design and code developing, 1D and 3D computational fluid dynamics, reconstruction, geometric analysis, mesh generation and surface data analysis for image-based modelling of blood vessels. I was involved as main developer of pyNS, an open-source framework for 0D/1D haemodynamic computational modelling.

From the beginning of 2011 to December 2013 I worked as freelancer for Orobix Srl. I was involved in software design and develop on cloud-based computing technologies as well as website coding (www.vmtk.org).

I’m based in Bergamo, Italy. You can reach me at simone (dot) manini (at) gmail (dot) com.

Publications

journal papers

Manini S, Antiga L, Botti L, Remuzzi A. pyNS, an open-source framework for 0D/1D hemodynamic modelling. Computational hemodynamics: Development of clinical tools for decision making, patient specific treatment and clinical management. Annals of Biomedical Engineering: Volume 43, Issue 6 (2015), Page 1461-1473.

Remuzzi A, Manini S. Computational model for prediction of fistula outcome. Journal of Vascular Access, 2014; 15(Suppl. 7): 64 - 69.

Kononowicz A, Narracott A, Manini S, Bayley M, Lawford PV, McCormack K, Zary N. A Framework for Different Levels of Integration of Computational Simulation into Web-Based Virtual Patients. Journal of Medical Internet Research, 2014;16(1):e23.

Caroli A(1), Manini S(1), Antiga L, Passera K, Ene-Iordache B, Rota S, Remuzzi G, Bode A, Leermakers J, Van de Vosse F, Vanholder R, Malovrh M, Tordoir J and Remuzzi A. Validation of patient specific hemodynamic computational model for planning vascular access surgery in hemodialysis patients. Kidney International (2013) 84, 1237–1245.

Manini S, Passera K, Huberts W, Botti L, Antiga L, Remuzzi A. Computational model for simulation of vascular adaptation following vascular access surgery in hemodialysis patients. Computer Methods in Biomechanics and Biomedical Engineering, Vol. 17, Iss. 12, 2014

Passera K, Manini S, Antiga L, Remuzzi A. Patient-specific model of arterial circulation for surgical planning of vascular access. Journal of Vascular Access, 2013; 14(2): 180 - 192.

conference papers

Manini S, Antiga L and Remuzzi A. Patient-specific multiscale simulation to plan vascular access surgery in hemodialysis patients. WCB 2014. Boston, July 2014.

Manini S, Antiga L, Huberts W and Remuzzi A. A clinical web-app for patient-specific multiscale simulations to plan vascular access surgery. ICCB 2013. Leuven, September 2013.

Manini S, Lanterna LA and Remuzzi A. Multiscale haemodynamic simulation of A1 and ACoA fenestrations and aneurysm growth. European Society of Biomechanics, Patras, August 2013.

Manini S, Antiga L, Huberts W and Remuzzi A. AVFSIM - A clinical web-application for patient-specific multi-scale hemodynamic simulations to plan vascular access surgery in hemodialysis patients. Modelling of Physiological Flows 2013. Chia Laguna, June 2013.

Manini S, Caroli A, Antiga L, Remuzzi A. AVFSIM, a web-application for planning vascular access surgery in hemodialysis patients. ASN Kidney Week 2012. San Diego, November 2012.

Manini S, Caroli A, Antiga L, Remuzzi A. Validation of patient specific multi-scale hemodynamic computational model for planning vascular access surgery in hemodialysis patients. ASN Kidney Week 2012. San Diego, November 2012.

Manini S, Caroli A, Antiga L, Rota S, Remuzzi A, Remuzzi G. Validation of patient specific multi-scale hemodynamic computational model for planning vascular access surgery in hemodialysis patients. VPH2012: International Conference on Computational Biomedicine - The Virtual Physiological Human Initiative Scientific Sessions 2012. London, September 2012.

Manini S, Antiga L, Botti L, Remuzzi A. Patient specific multi-scale hemodynamic computational model for planning vascular access surgery in hemodialysis patients. European Society of Biomechanics, Italian Chapter. Rome, June 2012.

Remuzzi A, Manini S, Passera K, Botti L, Huberts W, Antiga L. Patient specific multi-scale hemodynamic computational model for planning vascular access surgery in hemodialysis patients. Seventh International Biofluid Mechanics Symposium, Tel Aviv, May 2012.

Manini S, Antiga L, Huberts W, Botti L, Remuzzi A. pyNS, an open-source framework for 0D/1D hemodynamic modelling. CMBBE 2012 10th International Symposium, Berlin, April 2012.

Remuzzi A, Manini S, Passera K, Huberts W, Botti L, Antiga L. Computational Model for Simulation of Vascular Adaptation following Hemodialysis Vascular Access Surgery. ASN Kidney Week 2011, Philadelphia, November 2011.

Kroon W, Huberts W, Manini S, Bosboom M, Antiga L, Remuzzi A, van de Vosse F. Development of a network model to support surgical planning of vascular access creation for dialysis treatment. VPH 2010, Bruxelles, September 2010.